Zacherle in the Czech Republic
There are Zacherle's living in the Czech Republic. I was in contact with one of them, and he told me that his family had to change their name into Zacherle during World War II. This is a sad story, but the essential point is that they are not related to any Zacherle outside of the Czech Republic.
Additionally, in the late 1700s there are some references to Zacherle's in the Czech Republic: on July 13, 1760 Mariana Zacherle was born in Sivice, Vyskov. On September 11, 1775 Antonin Zacherle was married in Tvarozna, Brno.